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Chronic Autoimmune Hepatitis (AIH) is often associated with liver damage and can contribute to fertility problems. One of the classifications of AIH is positive anti-nuclear antibodies (ana). While anti-nuclear antibodies are present in small amounts of the population (roughly 5%), high amounts of these antibodies are linked to fertility problems, including unexplained infertility and miscarriage. In fact, many women with high levels of anti-nuclear antibodies are unable to conceive or to carry a pregnancy to term. Irregular anti-nuclear antibodies levels are also linked to implantation failure and miscarriage due to the inflammation of the uterus and placenta connected with anti-nuclear antibodies. An abnormal presence of these cells in the body is also linked to a low pregnancy success rate for methods of assisted reproduction, especially intracytoplasmic sperm injection (ICSI) and in vitro fertilization (IVF) — however these are still options that we could talk to you about. Please consider contacting us for a consultation.
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