Did you know that New Hope Fertility Center has high success rates for both Conventional IVF and Mini IVF?
1 Ongoing pregnancy rates (defined as a pregnancy of 12+ weeks) for patients in the Conventional IVF arm of the study.
2 Ongoing pregnancy rates (defined as a pregnancy of 12+ weeks) for patients in the Mini-IVF arm of the study.
3 Pregnancy rates (defined as a pregnancy for any period of time) for patients, nationally, using both Conventional and Mini IVF protocols.
On Monday, October 21, 2014, our Medical Director, Dr. John Zhang, presented the findings of a clinical research study at the American Society for Reproductive Medicine conference in Honolulu, Hawaii. The study, which was years in the making, indicates that Minimal Ovarian Stimulation (Mini-IVF) utilizing frozen single embryo transfer significantly lowers the risk of multiple gestations and completely eliminates Ovarian hyper stimulation syndrome (OHSS) compared to conventional IVF approaches.
A previous Dutch study compared conventional IVF treatments with a mild stimulation approach that differed from mini-IVF. “Our study,” says Zhang, “is the first to compare conventional and mini-IVF. The study’s strength is bolstered by the fact that it had a large sample size and a small number of patients who withdrew. Our patient population also included women of various ethnicities so the results are more generalizable. While pregnancy rates are lower, we can now say that mini-IVF approaches are likely to result in less treatment burden for patients, especially as it relates to cost.”
In terms of the ongoing pregnancy rates, while the couples in the minimal stimulation arm of the study were lower (50.5%) compared with couples in the conventional IVF arm (66.5%), these are easily explained by looking at the number of embryos transferred (1 in the minimal stimulation arm vs. 1.75 in the conventional arm). Live birth rates were comparable when adjusted for the number of embryos transferred and the major differences that occur deal primarily with the unfavorable side effects associated with conventional protocols.